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<td><span style="font-family:Helvetica, sans-serif; font-size:20px;font-weight:bold;">Science Daily Mind & Brain Daily Digest (Unofficial)</span></td>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414162216.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">New study finds surprising way to curb college-aged drinking harms -- without cutting alcohol</a>
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<p>Researchers have developed and tested an intervention called Counter-Attitudinal Advocacy and compared it to to the well-established Personalized Normative Feedback (PNF) to evaluate their effectiveness in decreasing drinks per week, peak blood alcohol concentration and alcohol-related consequences relative to a control group.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414162211.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Researchers may have solved decades-old mystery behind benzodiazepine side effects</a>
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<p>Identifying a key protein's role could improve the common mental health medications and point to new treatments for inflammation-related diseases, a medicinal chemist says.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414162049.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">LSD analogue with potential for treating schizophrenia developed</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 16:20</div>
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<p>Researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic's therapeutic power with reduced hallucinogenic potential.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414134922.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">AI tool to better assess Parkinson's disease, other movement disorders</a>
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<p>A groundbreaking open-source computer program uses artificial intelligence to analyze videos of patients with Parkinson's disease and other movement disorders. The tool, called VisionMD, helps doctors more accurately monitor subtle motor changes, improving patient care and advancing clinical research.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124825.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Gestational diabetes linked to ADHD in children</a>
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<p>A new study has found children born to mothers who experienced gestational diabetes (GDM) during pregnancy are more likely to develop attention-deficient hyperactive disorder (ADHD) and externalizing behavior.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124817.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Scientists identify key enzyme in Alzheimer's disease that links brain inflammation to memory loss</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 12:48</div>
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<p>A research team has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study provides critical insights into how astrocytes contribute to cognitive decline by producing excessive amounts of the inhibitory neurotransmitter GABA.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124723.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Rise and shine: Natural light lessens morning fatigue</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 12:47</div>
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<p>Researchers tested whether introducing light into the bedroom before waking would improve morning wakefulness and found an amount of time that seems to help fight off fatigue and raise alertness most.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124710.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Sleep matters: Duration, timing, quality and more may affect cardiovascular disease risk</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 12:47</div>
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<p>Healthy sleep includes multiple components, such as number of hours of sleep per night, how long it takes to fall asleep, daytime functioning and self-reported sleep satisfaction, and addressing these different dimensions of sleep may help to reduce cardiometabolic health and related risk factors, according to a new scientific statement.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124657.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Stress, depression factor into link between insomnia, heavy drinking</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 12:46</div>
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<p>A new study suggests that perceived stress and depression factor into the relationship between insomnia and hazardous drinking -- perhaps not a surprise. But because the relationship between insomnia and heavy drinking goes in both directions, the influence of stress or depression depends on which condition came first, the analysis found.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250414124345.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">How the brain controls movement under uncertainty</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 14th 2025, 12:43</div>
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<p>A new study by neuroscientists shows that our brain deals with different forms of visual uncertainty during movements in distinct ways. Depending on the type of uncertainty, planning and execution of movements in the brain are affected differently. These findings could help to optimize brain-computer interfaces that, for example, help people with paralysis to control prostheses or computers with their thoughts alone.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250411175718.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Candidate deafness genes revealed in new study</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 11th 2025, 17:57</div>
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<p>New candidate genes which could be responsible for deafness have been identified.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250411175449.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">New key genes in Parkinson's disease identified using CRISPR technology</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 11th 2025, 17:54</div>
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<p>A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not. The prevailing theory has suggested additional genetic factors may play a role. To address this question, a new study used modern technology, called CRISPR interference, to systematically examine every gene in the human genome. The scientists identified a new set of genes that contribute to the risk of Parkinson's disease, which opens the door to previously untapped drug targets for treating PD.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250411110035.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Police officers face twice the risk of traumatic brain injuries and PTSD, survey finds</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 11th 2025, 11:00</div>
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<p>Police officers are more than twice as likely to have traumatic brain injuries compared to the general population.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250410160955.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Brain study increases understanding of what triggers drug use relapse</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 10th 2025, 16:09</div>
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<p>Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and thereby the formation of strong drug-related memories, which can trigger relapse in individuals with substance use disorders (SUDs). The study, detailing these epigenetic mechanisms in the brain, uncovers a new molecular target for the development of novel SUD treatments.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250410160838.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Scientists develop process using molecules in the cell to identify environmental signals</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 10th 2025, 16:08</div>
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<p>Scientists have transformed RNA, a biological molecule present in all living cells, into a biosensor that can detect tiny chemicals relevant to human health. Research by scientists centers on RNA, a nucleic acid that plays a crucial role in most cellular processes. Their work is expected to have applications in the surveillance of environmental chemicals and, ultimately, the diagnosis of critical diseases including neurological and cardiovascular diseases and cancer.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250410160835.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Study provides scaffold to selectively target drug breakdown process</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 10th 2025, 16:08</div>
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<p>Scientists explored selectively blocking the CYP3A4 protein responsible for breaking down large swaths of approved drugs, providing a way to improve drug efficacy.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250410160714.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Brain pathway links inflammation to loss of motivation, energy in advanced cancer</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 10th 2025, 16:07</div>
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<p>Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that starts with neurons (labeled in green, above) that sense inflammation signals, and the researchers were able to treat the loss of motivation by blocking this pathway.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/04/250409154601.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">More people now die at home after stroke than in medical facilities</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Apr 9th 2025, 15:46</div>
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<p>A new analysis finds a significant uptick in the number of people dying at home due to ischemic stroke compared to inpatient medical facilities, and when not at home, individuals in rural communities and Black Americans were more likely to die in less specialized care environments. Additionally, the researchers found that after a steady 10-year decline, overall death rates from stroke are now rising.</p>
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<p><strong>Forwarded by:<br />
Michael Reeder LCPC<br />
Baltimore, MD</strong></p>
<p><strong>This information is taken from free public RSS feeds published by each organization for the purpose of public distribution. Readers are linked back to the article content on each organization's website. This email is an unaffiliated unofficial redistribution of this freely provided content from the publishers. </strong></p>
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