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<td><span style="font-family:Helvetica, sans-serif; font-size:20px;font-weight:bold;">Science Daily Mind & Brain Daily Digest (Unofficial)</span></td>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114181717.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Researchers invent soft, bioelectronic sensor implant</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 18:17</div>
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<p>Scientists describe their construction of complementary, internal, ion-gated, organic electrochemical transistors that are more amenable chemically, biologically and electronically to living tissues than rigid, silicon-based technologies. The medical device based on these transistors can function in sensitive parts of the body and conform to organ structures even as they grow. The result is a biocompatible sensor that can monitor brain functions in pediatric patients as they develop and grow.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114181702.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Gene editing extends lifespan in mouse model of prion disease</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 18:17</div>
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<p>Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60 percent. The work demonstrates that lowering levels of the prion protein improves lifespan in animals that have been infected with a human version of the protein.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114125250.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Hearing impairment may be a sign of increased risk of Parkinson's disease</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 12:52</div>
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<p>There may be a link between hearing impairment and an increased risk of developing Parkinson's according to new research. This is one of the first studies to examine whether sensory impairments, such as hearing loss, might increase the risk for Parkinson's or serve as an early warning sign. Parkinson's UK reports that an estimated 153,000 people in the UK currently live with Parkinson's, which is the fastest-growing neurological condition in the world.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114125129.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Scientists uncover rapid-acting, low-side-effect antidepressant target</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 12:51</div>
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<p>Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting therapeutics with minimal side effects. Researchers have previously demonstrated antidepressant-like effects of delta opioid receptor agonists in rodents. In their latest study, they uncover the molecular and cellular mechanism underlying its action that can advance its therapeutic development.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114124921.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">AI innovation unlocks non-surgical way to detect brain cancer spread</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 12:49</div>
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<p>Researchers have developed an artificial intelligence (AI) model to detect the spread of metastatic brain cancer using MRI scans, offering insights into patients' cancer without aggressive surgery.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114124912.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Genetic risks for age-related macular degeneration</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 12:49</div>
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<p>Age-related macular degeneration (AMD), which affects about 200 million people worldwide and can result in legal blindness, impairs an area of the eye (retina) used for reading, driving and many other critical daily tasks. A new study of large existing patient datasets indicates genetic and demographic factors that increase the risk for developing AMD.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250114124756.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Global study pinpoints genes for depression across ethnicities</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 14th 2025, 12:47</div>
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<p>New genetic risk factors for depression have been identified across all major global populations for the first time, allowing scientists to predict risk of depression regardless of ethnicity. The world's largest and most diverse genetic study ever into major depression has revealed nearly 300 previously unknown genetic links to the condition, experts say.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250113134202.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Study uses design features of the ICU to evaluate delirium</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 13th 2025, 13:42</div>
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<p>ICU delirium can be associated with a multitude of factors including underlying and acute medical conditions, pharmacologic agents or treatment regimens like surgery. Currently there is no definitive consensus on drug interventions that aid in the prevention of delirium or its treatment. While there has been some evidence that the ICU environment plays a role in delirium, more research is needed to understand this association. Researchers found windowed patient rooms were associated with an increase in the odds of developing delirium, when compared to patient rooms without windows.</p>
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<td><a href="https://www.sciencedaily.com/releases/2025/01/250113134146.htm" style="font-family:Helvetica, sans-serif; letter-spacing:-1px;margin:0;padding:0 0 2px;font-weight: bold;font-size: 19px;line-height: 20px;color:#222;">Changes in opioid use outcomes after passage of medical marijuana laws</a>
<div style="font-family:Helvetica, sans-serif; text-align:left;color:#999;font-size:11px;font-weight:bold;line-height:15px;">Jan 13th 2025, 13:41</div>
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<p>A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show decreases in opioid outcomes after medical marijuana laws existed among people reporting cannabis use.</p>
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<p><strong>Forwarded by:<br />
Michael Reeder LCPC<br />
Baltimore, MD</strong></p>
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